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Trends in Biosafety and Biosecurity

Renchu Guan1,2, ###1, Yanchun Liang1,2, Dong Xu3 , ###1 , Xiaoyue Feng1,*

1 Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education, College of Computer Science and Technology, Jilin University, Changchun 130012, China
2 Zhuhai Laboratory of Key Laboratory of Symbolic Computation and Knowledge Engineering of Education, Zhuhai College of Jilin University, Zhuhai 519041, China
3 Department of Electric Engineering and Computer Science, and Christopher S. Bond Life Sciences CenterUniversity of Missouri, Columbia, USA

* Corresponding author, E-mail:


Up to October 13, 2020, 37,948,577 cases of Corona Virus Disease 2019 (COVID-19) have been reported worldwide (1080,619 deaths), and there is a further development trend. The problems reflected in this epidemic have made biosafety and biosecurity (hereafter collectively referred to as "biosafety") once again a hot topic of discussion in the international community. Biosafety covers a wide range, and it is very important to be able to quickly retrieve biosafety hotspots and trends from massive data. We designed and constructed a novel model LDAPR to extract topics from the abstracts of biosafety-related papers from 2011 to 2020, and we conducted hotspot and trend analysis on the results of LDAPR. At the same time, we have carried out further research on the connections of these topics, and these connections will provide inspiration for further research. Our results are freely available at